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〒020-8505 盛岡市内丸19-1
心血管・腎・内分泌内科

研究業績 （2010年～）

  2. Koeda Y, Komatsu T, Matsuura Y, Morioka H, Uchimura Y, Taguchi Y, Tanaka K, Kawakami J, Nakamura M, Takahashi S, Takahashi Y, Naganuma Y, Endo H, Ito T, Morino Y, Nakamura M. CHADS2 and modified CHA2DS2-VASc scores for the prediction of congestive heart failure in patients with nonvalvular atrial fibrillation. J Arrhythm. 2017 Oct;33(5):488-493.

  3. Omama S, Ogasawara K, Ishibashi Y, Nakamura M, Tanno K, Sakata K. The Impact and Effectivity of an Inventory Survey for a Stroke Registry in Iwate Prefecture. J Stroke Cerebrovasc Dis. 2017 Oct;26(10):2160-2166.

  4. Nakamura M, Tanaka K, Tanaka F, Matsuura Y, Komi R, Niiyama M, Kawakami M, Koeda Y, Sakai T, Onoda T, Itoh T; Northern Iwate Heart Registry Consortium. Long-Term Effects of the 2011 Japan Earthquake and Tsunami on Incidence of Fatal and Nonfatal Myocardial Infarction. Am J Cardiol. 2017 Aug 1;120(3):352-358.

  5. Satoh M, Nasu T, Takahashi Y, Osaki T, Hitomi S, Morino Y, Nakamura M. Expression of miR-23a induces telomere shortening and is associated with poor clinical outcomes in patients with coronary artery disease. Clin Sci (Lond). 2017 Jul 13;131(15):2007-2017.

  6. Nakamura M, Tanaka F, Segawa T, Takahashi T, Matsuura Y, Sakai T, Nishiyama O, Niiyama M, Onoda T, Koshiyama M; (on behalf of Northern Iwate Heart Disease Registry Consortium). Temporal Trends in the Incidence and Clinical Features of Acute Myocardial Infarction in a Japanese Rural Area From 2006 to 2014. Circ J. 2017 Jul 1.

  7. Nakamura M, Tanaka F, Komi R, Tanaka K, Onodera M, Kawakami M, Koeda Y, Sakai T, Tanno K, Onoda T, Matsura Y, Komatsu T; Northern Iwate Heart Registry Consortium. Sustained Increase in the Incidence of Acute Decompensated Heart Failure After the 2011 Japan Earthquake and Tsunami. Am J Cardiol. 2016; 118(9):1374-1379.

  8. Takahashi S, Nakamura M, Yonekura Y, Tanno K, Sakata K, Ogawa A, Kobayashi S.Association between relocation and changes in cardiometabolic risk factors: a longitudinal study in tsunami survivors of the 2011 Great East Japan Earthquake. BMJ Open. 2016 May 12;6(5):e011291.

  9. Koeda Y, Tanaka F, Segawa T, Ohta M, Ohsawa M, Tanno K, Makita S, Ishibashi Y, Itai K, Omama S, Onoda T, Sakata K, Ogasawara K, Okayama A, Nakamura M.:Comparison between urine albumin-to-creatinine ratio and urine protein dipstick testing for prevalence and ability to predict the risk for chronic kidney disease in the general population (Iwate-KENCO study): a prospective community-based cohort study. BMC Nephrol. 2016 May 12;17(1):46.

  10. Tanaka F, Komi R, Makita S, Onoda T, Tanno K, Ohsawa M, Itai K, Sakata K, Omama S, Yoshida Y, Ogasawara K, Ishibashi Y, Kuribayashi T, Okayama A, Nakamura M; Iwate-Kenco Study Group.Low-grade albuminuria and incidence of cardiovascular disease and all-cause mortality in nondiabetic and normotensive individuals. J Hypertens. 2016 Mar;34(3):506-12.

  11. Honma M, Tanaka F, Sato K, Onoda T, Sakai T, Nishiyama O, Matsumoto T, Onodera M, Sakata K, Nakamura M, on behalf of Northern Iwate Heart Disease Registry. Consortium.:Sex-specific temporal trends in the incidence and prevalence of hospitalized patients with preserved versus reduced left ventricular ejection fraction heart failure: A Japanese community-wide study. International Journal of Cardiology Heart & Vasculature 2015;9:15-21.

  12. Ozawa M, Komatsu T, Sato Y, Kunugita F, Tachibana H, Tashiro A, Okabayashi H, Nakamura M.:Comparison of the effects of bepridil and aprindine for the prevention of atrial fibrillation after cardiac and aortic surgery: A prospective randomized study. J Arrhythm. 2015 Oct;31(5):302-6.

  13. Satoh M, Takahashi Y, Tabuchi T, Minami Y, Tamada M, Takahashi K, Itoh T, Morino Y, Nakamura M.:Cellular and molecular mechanisms of statins: an update on pleiotropic effects. Clin Sci (Lond). 2015 Jul;129(2):93-105.

  14. Takegami M, Miyamoto Y, Yasuda S, Nakai M, Nishimura K, Ogawa H, Hirata K, Toh R, Morino Y, Nakamura M, Takeishi Y, Shimokawa H, Naito H.Comparison of cardiovascular mortality in the Great East Japan and the Great Hanshin-Awaji Earthquakes　- a large-scale data analysis of death certificates. Circ J. 2015;79(5):1000-8.

  15. Itoh T, Fusazaki T, Kimura T, Oikawa H, Sasou S, Ishikawa Y, Goto I, Komuro K, Nakajima S, Koeda Y, Kaneko K, Nishiyama O, Nakamura M, Morino Y.:Clinical and pathological characteristics of homogeneous and nonhomogeneous tissue of in-stent restenosis visualized by optical coherence tomography. Coron Artery Dis. 2015 May;26(3):201-11.

  16. Tanaka F，Makita S，Ito T，Onoda T，Sakata K，Nakamura M.:Relationship between the seismic scale of the 2011 northeast Japan earthquake and the incidence of acute myocardial infarction: A population-based study. Am Heart J. 2015;169(6):861-869.

  17. Satoh M，Takahashi Y， Tabuchi T，Tamada M，Takahashi K，Itoh T，Morino Y，Nakamura M.:Circulating Toll-like receptor 4-responsive microRNA panel in patients with coronary artery disease: Results from prospective and randomized study of treatment with renin-angiotensin system blockades. Clin Sci. 2015;128:483-491.

  18. Omama S, Yoshida Y, Ogasawara K, Ogawa A, Ishibashi Y, Nakamura M, Tanno K, Ohsawa M, Onoda T, Itai K, Sakata K.:Extent of flood damage increased cerebrovascular disease incidences in Iwate prefecture after the great East Japan earthquake and tsunami of 2011. Cerebrovasc Dis. 2014;37(6):451-9.

  19. Koeda Y, Tanaka F, Segawa T, Ohta M, Ohsawa M, Tanno K, Makita S, Ishibashi Y, Omama S, Onoda T, Nakamura M.:Usefulness of risk grading system using albuminuria for predicting cardiovascular events and all-cause death in chronic kidney disease: a population-based prospective cohort study in Japan. Int J Cardiol. 2014 Aug 20;175(3):576-7.

  20. Niiyama M, Tanaka F, Nakajima S, Itoh T, Matsumoto T, Kawakami M, Naganuma Y, Omama S, Komatsu T, Onoda T, Sakata K, Ichikawa T, Nakamura M.:Population-based incidence of sudden cardiac and unexpected death before and after the 2011 earthquake and tsunami in Iwate, northeast Japan. J Am Heart Assoc. 2014 May 8;3(3):e000798.

  21. Ishisone T，Satoh M，Okabayashi H，Nakamura M.:Usefulness of multidetector CT angiography for anomalous origin of coronary artery. BMJ Case Reports. published online 22 August 22;2014.

  22. Kumagai A，Tashiro A，Abiko A，Kamada T，Okabayashi H，Nakamura M.:Usefulness of transesophageal echocardiography in diagnosis of hemolytic anemia post total aortic arch replacement using the elephant trunk technique. Journal of Echocardiography. 2014;12(3):115-117.

  23. Makita S，Onoda T，Ohsawa M，Tanno K，Tanaka F，Omama S，Yoshida Y，Ishibashi Y，Itai K，Sakata K，Ohta M，Kuribayashi T，Ogasawara K，Ogawa A，Okayama A，Nakamura M.:Bradycardia is associated with future cardiovascular diseases and death in men from the general population. Atherosclerosis. 2014;236(1):116-20.

  24. Komatsu T，Sato Y，Ozawa M，Kunugita F，Yoshizawa R，Morino Y，Nakamura M.:Comparison between CHADS2 and CHA2DS2-VASc score for risk stratification of ischemic stroke in Japanese patients with non-valvular paroxysmal atrial fibrillation not receiving anticoagulant therapy. Int Heart J. 2014;55(2):119-25.

  25. Itoh T， Nakajima S，Tanaka F，Nishiyama O， Matsumoto T，Endo H，Sakai T，Nakamura M，Morino Y.:Impact of the Japan earthquake disaster with massive Tsunami on emergency coronary intervention and in-hospital mortality in patients with acute ST-elevation myocardial infarction..Eur Heart J Acute Cardiovasc Care. 2014 Sep;3(3):195-203.

  26. Suzuki Y，Nishiyama O，Sakai T，Niiyama M，Itoh T，Nakamura M.:Acute Coronary Syndrome Caused by Coronary Vasospasms Associated with Churg-Strauss Syndrome:Effects Of Betamethasone Therapy. Internal Medicine. 2014;53:717-720.

  27. Koeda C，Tashiro A，TakahashiT，Niiyama M，Sakamoto R，KimuraT，Morino Y，Terui K，Tanaka R，Yoshioka K，Kin H，Okabayashi H，Nakamura M.:Possible Usefulness of Gadolinium-Enhanced Brain MRI for Evaluating Risk of Perioperative Hemorrhage: A Case of Infective Endocarditis. Case Reports in Cardiology. 2014:158041.

  28. Sato K，Segawa T，Takahashi T，Tanno K，Ohsawa,M， Onoda T， Sakata K，Omama S，Ogasawara K，Ishibashi Y，Makita S，Okayama A，Nakamura M.:Cardiovascular risk stratification with plasma B-type natriuretic peptide levels in a community-based hypertensive cohort. Am J Cardiol. 2014;113(4):682-686.

  29. Makita S，Nakamura M.:Possible Clinical Aspects Of a linkage of Preceding Weight Loss and Heart Failure. Circulation Journal. 2014;78(3):590-591.

  30. Komatsu T，Sato Y，Ozawa M， Kunugita F，Yoshizawa R，Morino Y， Nakamura M.:Comparison between CHADS2 and CHA2DS2-VASc score for risk stratification of ischemic stroke in Japanese patients with non-valvular paroxysmal atrial fibrillation not receiving anticoagulant therapy.Int Heart J. 2014;55(2):119-125.

  31. Satoh M, Tabuchi T, Itoh T, Nakamura M. NLRP3 inflammasome activation in coronary artery disease: results from prospective and randomized study of treatment with atorvastatin or rosuvastatin. Clin Sci (Lond). 2014;126(3):233-41.

  32. Sato K, Segawa T, Tanaka F, Takahashi T, Tanno K, Ohsawa M, Onoda T, Itai K, Sakata K, Omama S, Ogasawara K, Ishibashi Y, Makita S, Okayama A, Nakamura M. Cardiovascular Risk Stratification With Plasma B-Type Natriuretic Peptide Levels in a Community-Based Hypertensive Cohort. Am J Cardiol. 2014 Feb 15;113(4):682-6.

  33. Koeda Y, Itoh T, Fusazaki T, Nakamura M, Morino Y. A unique stenosis in saphenous vein graft visualized by optical coherence tomography. Heart Vessels. 2014;29(2):278-81.

  34. Tanaka F, Makita S, Onoda T, Tanno K, Ohsawa M, Itai K, Sakata K, Omama S, Yoshida Y, Ogasawara K, Ogawa A, Ishibashi Y, Kuribayashi T, Okayama A, Nakamura M; Iwate-Kenco Study Group. Predictive value of lipoprotein indices for residual risk of acute myocardial infarction and sudden death in men with low-density lipoprotein cholesterol levels <120 mg/dl. Am J Cardiol. 2013;112:1063-8.

  35. Nakamura M, Koeda Y, Tanaka F, Onoda T, Itai K, Ohsawa M, Tanno K, Sakata K, Omama S, Ishibashi Y, Makita S, Ohta M, Ogasawara K, Komatsu T, Okayama A. Plasma B-type Natriuretic Peptide as a Predictor of Cardiovascular Events in Subjects with Atrial Fibrillation: A Community-Based Study. PLoS One. 2013;8:e81243.

  36. Ishisone T, Koeda Y, Tanaka F, Sato K, Nagano M, Nakamura M. Comparison of utility of arterial stiffness parameters for predicting cardiovascular events in the general population. Int Heart J. 2013;54:160-5.

  37. Makita S, Abiko A, Nagai M, Yonezawa S, Koshiyama M, Ohta M, Nakamura M. Influence of daily alcohol consumption on serum adiponectin levels in men. Metabolism. 2013;62(3):411-6.

  38. Koeda C, Tashiro A, Itoh T, Okabayashi H, Nakamura M. Mild renal dysfunction on admission is an important prognostic predictor in patients with infective endocarditis: a retrospective single-center study. Intern Med. 2013;52(10):1013-8.

  39. Komatsu T, Sato Y, Ozawa M, Kunugita F, Ueda H, Tachibana H, Morino Y, Nakamura M. Relationship between CHADS2 score and efficacy of antiarrhythmic drug therapy in patients with paroxysmal atrial fibrillation. Circ J. 2013;77(3):639-45.

  40. Makita S, Onoda T, Ohsawa M, Tanaka F, Segawa T, Takahashi T, Satoh K, Itai K, Tanno K, Sakata K, Omama S, Yoshida Y, Ishibashi Y, Koyama T, Kuribayashi T, Ogasawara K, Ogawa A, Okayama A, Nakamura M. Influence of mild-to-moderate alcohol consumption on cardiovascular diseases in men from the general population. Atherosclerosis. 2012;224:222-7.

  41. Nagai M, Makita S, Abiko A, Nakamura M. Factors related to long-term prognosis in medically treated type B aortic dissection: a physical predisposing factor. Int Angiol. 2012;31(5):427-32.

  42. Nakamura M, Tanaka F, Nakajima S, Honma M, Sakai T, Kawakami M, Endo H, Onodera M, Niiyama M, Komatsu T, Sakamaki K, Onoda T, Sakata K, Morino Y, Takahashi T, Makita S. Comparison of the incidence of acute decompensated heart failure before and after the major tsunami in Northeast Japan. Am J Cardiol. 2012;110:1856-60.

  43. Tabuchi T, Satoh M, Itoh T, Nakamura M. MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression. Clin Sci (Lond). 2012;123(3):161-71.

  44. Komatsu T. Current strategies of antiarrhythmic drug therapy for paroxysmal atrial fibrillation. J Arrhythmia. 2012;28(3):162-169.

  45. Onodera M, Nakamura M, Tanaka F, Takahashi T, Makita S, Ishisone T, Ishibashi Y, Itai K, Onoda T, Ohsawa M, Tanno K, Sakata K, Omama S, Ogasawara K, Ogawa A, Kuribayashi T, Sakamaki K, Okayama A. Plasma B-type natriuretic peptide is useful for cardiovascular risk assessment in community-based diabetes subjects: comparison with albuminuria. Int Heart J. 2012;53(3):176-81.

  46. Komatsu T, Tachibana H, Satoh Y, Ozawa M, Kunugita F, Ueda H, Nakamura M. Relationship between CHA(2)DS(2)-VASc scores and ischemic stroke/cardiovascular events in Japanese patients with paroxysmal atrial fibrillation not receiving anticoagulant therapy. J Cardiol. 2012;59(3):321-8.

  47. Satoh M, Tabuchi T, Minami Y, Takahashi Y, Itoh T, Nakamura M. Expression of let-7i is associated with Toll-like receptor 4 signal in coronary artery disease: effect of statins on let-7i and Toll-like receptor 4 signal. Immunobiology. 2012;217(5):533-9.

  48. Takahashi Y, Satoh M, Tabuchi T, Nakamura M. Prospective, randomized, single-blind comparison of effects of 6 months' treatment with atorvastatin versus pravastatin on leptin and angiogenic factors in patients with coronary artery disease. Heart Vessels. 2012;27(4):337-43.

  49. Nakamura M, Tanaka F, Takahashi T, Makita S, Ishisone T, Onodera M, Ishibashi Y, Itai K, Onoda T, Ohsawa M, Tanno K, Sakata K, Shinichi O, Ogasawara K, Ogawa A, Kuribayashi T, Okayama A. Sex-specific threshold levels of plasma B-type natriuretic peptide for prediction of cardiovascular event risk in a Japanese population initially free of cardiovascular disease. Am J Cardiol. 2011;108:1564-9.

  50. Koeda Y, Nakamura M, Tanaka F, Onoda T, Itai K, Tanno K, Ohsawa M, Makita S,Ishibashi Y, Koyama T, Yoshida Y, Omama S, Ogasawara K, Ogawa A, Kuribayashi T,Okayama A. Serum C-reactive protein levels and death and cardiovascular events in mild to moderate chronic kidney disease. Int Heart J. 2011;52(3):180-4.

  51. Abiko A, Makita S, Naganuma Y, Nagai M, Nakamura M. Association between metabolic syndrome and carotid atherosclerosis: relevance of combined criteria including the serum adiponectin level for the general population. Intern Med. 2011;50(5):381-7.

  52. Komatsu T, Tachibana H, Sato Y, Ozawa M, Kunugita F, Nakamura M. Long-term efficacy of upstream therapy with lipophilic or hydrophilic statins on antiarrhythmic drugs in patients with paroxysmal atrial fibrillation: comparison between atorvastatin and pravastatin. Int Heart J. 2011;52(6):359-65.

  53. Komatsu T, Tachibana H, Sato Y, Ozawa M, Kunugita F, Nakamura M. Long-term efficacy of amiodarone therapy for the prevention of recurrence of paroxysmal atrial fibrillation. Analysis based on patient characteristics. Int Heart J. 2011;52(4):212-7.

  54. Satoh M, Minami Y, Takahashi Y, Tabuchi T, Nakamura M. A cellular microRNA, let-7i, is a novel biomarker for clinical outcome in patients with dilated cardiomyopathy. J Card Fail. 2011;17(11):923-9.

  55. Goto I, Itoh T, Kimura T, Fusazaki T, Matsui H, Sugawara S, Komuro K, NakamuraM. Morphological and quantitative analysis of vascular wall and neointimalhyperplasia after coronary stenting. Circ J. 2011 Jun 24;75(7):1633-40.

  56. Komatsu T, Tachibana H, Satoh Y, Ozawa M, Kunugita F, Nakamura M. Clinical profiles, efficacy of antiarrhythmic drug therapy, and cardiovascular prognosisin patients with first detected paroxysmal atrial fibrillation. Int Heart J. 2011;52(1):32-8.

  57. Kanno H, Segawa T, Miura Y, Miyata M, Yoshida A, Nakamura M, Sawai T. Systemicsclerosis presented as congestive heart failure: an autopsy case. Mod Rheumatol. 2011;21(4)423-7.

  58. Tanaka F, Makita S, Onoda T, Tanno K, Ohsawa M, Itai K, Sakata K, Onodera M, Koeda Y, Kawarura K, Terayama Y, Yoshida Y, Ogawa A, Okayama A, Nakamura M;Iwate-KENCO Study Group. Prehypertension subtype with elevated C-reactiveprotein: risk of ischemic stroke in a general Japanese population. Am JHypertens. 2010;23:1108-13.

  59. Sakuma M, Nakamura M, Tanaka F, Onoda T, Itai K, Tanno K, Ohsawa M, Sakata K, Yoshida Y, Kawamura K, Makita S, Okayama A. Plasma B-type natriuretic peptide level and cardiovascular events in chronic kidney disease in a community-based population. Circ J. 2010;74:792-7.

  60. Nakamura M, Tanaka F, Onoda T, Takahashi T, Sakuma M, Kawamura K, Tanno K, Ohsawa M, Itai K, Sakata K, Makita S; Iwate KENCO Study Groups. Gender-specific risk stratification with plasma B-type natriuretic peptide for future onset of congestive heart failure and mortality in the Japanese general population. Int J Cardiol. 2010;143:124-9.

  61. Makita S, Matsui H, Naganuma Y, Abiko A, Tamada M, Nakamura M. Diabetic state as a crucial factor for impaired arterial elastic properties in patients with peripheral arterial disease. Atherosclerosis. 2010;208(1):167-70.

  62. Tamada M, Makita S, Abiko A, Naganuma Y, Nagai M, Nakamura M. Low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio as a useful marker for early-stage carotid atherosclerosis. Metabolism. 2010;59(5):653-7.

  63. Makita S, Abiko A, Naganuma Y, Nagai M, Nakamura M. Chronic kidney disease is associated with increased carotid artery stiffness without morphological changes in participants of health check-up programs. Atherosclerosis. 2010;213(1):306-10.

  64. Komatsu T, Tachibana H, Satoh Y, Ozawa M, Kunugida F, Nakamura M. Relationshipbetween the long-term preventive effect of combined treatment with antiarrhythmicdrugs plus angiotensin-converting enzyme inhibitors and circadian variation inthe onset of paroxysmal atrial fibrillation. Int Heart J. 2010;51(5):331-6.

  65. Komatsu T, Tachibana H, Satoh Y, Ozawa M, Kunugita F, Tashiro A, OkabayashiH, Nakamura M. Prospective comparative study of intravenous cibenzoline anddisopyramide therapy in the treatment of paroxysmal atrial fibrillation aftercardiovascular surgery. Circ J. 2010 Sep;74(9):1859-65.

  66. Itoh T, Fukami K, Suzuki T, Kimura T, Kanaya Y, Orii M, Goto I, Matsui H,Sugawara S, Nakajima S, Fusazaki T, Nakamura M; IMPORTANT investigators.Comparison of long-term prognostic evaluation between pre-interventionthrombolysis and primary coronary intervention: a prospective randomized trial:five-year results of the IMPORTANT study. Circ J. 2010 Aug;74(8):1625-34. Epub2010 Jun 19. Erratum in: Circ J. 2010 Sep;74(9):2027.

  67. Takahashi Y, Satoh M, Minami Y, Tabuchi T, Itoh T, Nakamura M. Expression of miR-146a/b is associated with the Toll-like receptor 4 signal in coronary artery disease: effect of renin-angiotensin system blockade and statins on miRNA-146a/b and Toll-like receptor 4 levels. Clin Sci (Lond). 2010 Jul 23;119(9):395-405.

  68. Kimura T, Itoh T, Fusazaki T, Matsui H, Sugawara S, Ogino Y, Endo H,Kobayashi K, Nakamura M. Low-density lipoprotein-cholesterol/high-densitylipoprotein-cholesterol ratio predicts lipid-rich coronary plaque in patientswith coronary artery disease--integrated-backscatter intravascular ultrasoundstudy. Circ J. 2010 Jul;74(7):1392-8.

  69. Satoh M, Minami Y, Takahashi Y, Tabuchi T, Nakamura M. Expression of microRNA-208 is associated with adverse clinical outcomes in human dilated cardiomyopathy. J Card Fail. 2010 May;16(5):404-10.

  70. Komatsu T, Tachibana H, Sato Y, Ozawa M, Kunugida F, Nakamura M. Efficacy of antiarrhythmic drug therapy in preventing recurrence of atrial fibrillation and long-term cardiovascular prognosis in patients with asymptomatic paroxysmal atrial fibrillation. Int Heart J. 2010 Mar;51(2):98-104.

  71. Komatsu T, Tachibana H, Sato Y, Ozawa M, Kunugida F, Orii M, Nakamura M. Relationship between CHADS2 score and ischemic stroke during rhythm control therapy for paroxysmal atrial fibrillation. Int Heart J. 2010 Jan;51(1):24-9.

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